FUNCTIONS OF GROWTH HORMONE

Everything from the concentrations of nutrients, electrolytes, water and hormones in the bloodstream to emotions, stress, and trauma impacts the hormonal system via the hypothalamus.  The hypothalamus then uses neural stimulation of the anterior pituitary gland to control GH release.  Unlike other hormones (with the exception of those of the thyroid), GH affects almost all body tissues.  GH is considered a master hormone which controls many organ and body functions.  GH also regulates itself.

The rejuvenating effects of GH are all-encompassing, acting on both the mind and the body.

• GH is the primary hormone responsible for stimulating tissue repair, cell replacement, brain function and enzyme production.
• GH is the ultimate anti-aging therapy and affects almost every cell in the body, rejuvenating the skin and bones, regenerating the heart, liver, lungs and kidneys, and bringing back organ and tissue function to more youthful levels.
• GH revitalizes the immune system, lowers the risk factors of heart attack and stroke, improves oxygen uptake and helps prevent osteoporosis.
• GH is a powerful anti-obesity hormone and acts to naturally enhance sexual function.
• For many, GH acts as a natural cosmetic, restoring skin elasticity, smoothing wrinkles and rejuvenating hair and nails.

• The rate of GH secretions can rise or fall within minutes, with the highest levels occurring after strenuous exercise and during deep sleep.
• Most other changes are usually related to the concentration of nutrients in the blood (protein, fat and sugar).
• The release of GH is also affected by stress, excitement and trauma.

IGF-1 AND ALBUMIN

The liver manufactures IGF-1 when stimulated by GH which in turn triggers the liver to produce albumin.  Many of the beneficial effects of GH are accomplished via albumin.  According to Dr. Kenneth Seaton, D. Sc., albumin is the "life factor" and one of the critical measures of our well-being and longevity.  Albumin is the dominant blood protein through which GH controls a vast army whose primary function is physiological balance (homeostasis).

CHARACTERISTICS OF ALBUMIN

• Viewed as the ultimate antioxidant
• Primary bio-marker of biological age
• Indicator of trend toward degenerative disease
• Essential for cell growth and renewal

• Regulates water metabolism
• Transports nutrients to cells
• Transports wastes from cells
• Assures proper elimination of wastes
• Synthesizes proteins
• Binds toxins and heavy metals
• Protects cells against shock
• Donates electrons to cells
• Transports and buffers excess levels of hormones
• Insures complete digestion of food
• Vital for central nervous system development
• Stabilizes blood through turnover of red blood cells
• Prevents red blood cells from "sticking" together (zeta potential)
• Balances blood pH

• The cell's transcription of DNA to form RNA, provided that all essential nutrients are available.
• Transport of most amino acids across the cell membranes.
• RNA translation by ribosomes, promoting protein synthesis in cytoplasm of cells.
• Reduction of tissue breakdown of amino acids and protein by mobilizing large amounts of free fatty acids from adipose tissue.
• Protein "sparing" and carbohydrate "saving".
• Efficiency in controlling blood sugar utilized by cells for energy.

Somatopause is the declining mid-life phase in the human life cycle during which reduced GH levels result in a noticeable reduction in physiological function.  During somatopause the cells and organs gradually dehydrate and diminish in size and function.  Somatopause usually begins when people reach their mid-forties but can start years earlier.  It's possible for some individuals in their forties to have IGF-1 levels usually expected of a person in their seventies and vice versa.  Lifestyles apparently play an important role, along with heredity and environment.  By the 60th birthday it is not uncommon to see declines from 60% to 75% of normal levels.  It's no wonder that so many middle-aged people report feeling old with little vitality.
 

IDEAL LEVELS OF IGF-1

GH is usually measured through IGF-1.  The ideal level of IGF-1 for most people over 35 years of age is 325-375 (ng/ml), although for some 375-450 may be ideal, and for others it may only reach 200-300.

TESTING FOR GH

GH levels in the body are tested indirectly through a Somatomedin-C or IGF-1 blood test (either name may be used by different labs).  Expect most individuals over 35 years of age to initially record IGF-1 levels of 100-200 ng/ml.  After 2 months, the majority will record a substantial increase in their IGF-1 levels, with about 20% showing a decrease in levels even while reporting tangible health improvements.  Regardless of the scores, most everyone taking APGL for a month or longer reports visible evidence of improvement in most aspects of their health.

Along with IGF-1, consider a blood and hormone panel such as the following: pregnenolone, thyroid (T3, T4, T7, TSH, TBG), progesterone, estrogens (estriol, estradiol, estrone), testosterone (free-, dihydro-, total-), DHEA, PSA, and CA-125.
 

CLINICAL STUDIES

"The overall deterioration of the body that comes with growing old is not inevitable." - Dr. Daniel Rudman

The Rudman study published in the New England Journal of Medicine in 1990 was the first using GH as an anti-aging compound.  The study divided 21 men with IGF-1 levels under 350 ng/ml of blood into two groups for a six-month period.  In the experimental group, the study showed an increase in lean muscle mass, a decrease in adipose fat tissue, and an increase in vertebral bone height, as well as measurable increases in IGF-1 blood levels.  The control group showed no gain in these areas.  The effects of six months of growth hormone were equivalent in magnitude to the regression of aging by 10-20 years.

Dr. Edmund Chein and L. Cas Terry, M.D., Ph. D., tested over 800 individuals over the age of 40, and reported in their 1995 study that GH had substantial benefits and virtually no side effects.  They reported no treatment failures.  Of great interest to Dr. Terry was the complete absence of cancer in his patients during the study.
 

RESULTS OF GH THERAPY

Numerous clinical studies have measured and highlighted the following results after six months or more of GH therapy:

• Improved memory and intellectual capacity
• Improvement in Alzheimer's and Parkinson's syndromes
• Regeneration of the brain, heart, liver, pancreas, spleen, kidneys and other organs
• Improved sexual drive and performance
• Increased fertility, sperm production and ovulation
• Enhanced immunity and resistance to infection
• Faster injury healing, including wounds and fractures
• Hair re-growth and color restoration
• Sharper vision
• Improved exercise tolerance and performance
• Increased muscle mass without exercise
• Reduction of excess cellulite and fat
• Increased energy, strength and stamina
• Reduction of high blood pressure
• Increase in HDL cholesterol
• Decrease in LDL cholesterol
• Strengthening of bones
• Reversal of osteoporosis
• Elevation of moods and reduction of depression
• Improved sleep (especially deep healing sleep)
• Improved skin elasticity and thickness
• Smoothing and reduction of facial wrinkles
• Improved mineral balance
• Anti-Aging (turning back of the biological clock)

SYNERGISTIC NUTRITION

APGL works best when used with synergistic nutrition.  Supplements which support GH levels are of three primary categories: precursors, stimulants and synergists.

• Precursors are the foundation "raw materials" from which the body produces its own GH.  Some precursors are the amino acids glycine, tryptophan, arginine, ornithine, lysine and glutamine.

• Stimulants directly or indirectly are responsible for the body's increased ability to stimulate GH.  Niacin (vitamin B-3) is a safe stimulant of GH, best used with other nutrients such as amino acids, vitamins and essential fatty acids.  The optimal dosage is 50-200 mg, 2-3 times per day.

• Synergists are substances which enhance the effects of, or work together with, GH by performing similar functions.  Potent synergists of GH include low dosages of hormones such as melatonin and DHEA which, with GH, seem to enhance oxidation and energy efficiency within the cells.  This energetic renewal is theorized by some to assist in improving protein synthesis of the DNA, thereby regenerating cells, tissues and organs.  The oxidation rate can be verified through tissue mineral analysis of the hair, blood, or saliva.

• Balanced nutrition: approximately 40% complex carbohydrates, 30% protein, 30% fat.
• Consumption of organic raw or lightly cooked fresh foods: fruits, vegetables (especially green leafy types), grains, nuts, seeds, fish, poultry.
• Limiting consumption of meats and processed-concentrated non-living foods: certain fats and oils, sugars, salt and alcohol. Living whole foods are best.
• Utilization of synergistic vitamins, minerals and amino acids.
• Drinking distilled or reverse-osmosis water. A day of liquids only will promote healing, cleansing, and organ function.
• Consistent exercise and strength training three times a week, such as brisk walking, swimming, dancing and active sports.
• Daily sunbath (without glasses) with as much exposed skin as feasible for 10-20 minutes.
• Sufficient sleep and rest
• Deep breathing of clean air

NUTRITION AND HORMONES

Individuals with low cholesterol levels (below 160) especially need fats and oils to make hormones.  The best sources are unrefined olive, coconut, whole fish, flax, black currant, evening primrose, borage, hemp and butter.
 

APGL FOR CHILDREN

Children should not be given APGL unless it has been prescribed by a doctor who has determined, through formal diagnosis which includes testing IGF-1, that they require it. APGL is convenient, effective and safe for children with serious growth disorders.
 

HOW TO TAKE APGL

The best time to take APGL is before meals, before bedtime and before workouts.